Finding a mouse in your home or business is enough to send anyone into a panic. And acting quickly is vital!
Addressing a rodent issue promptly is just as crucial to maintaining your property as scheduling regular house cleaning or seasonal mosquito control.
To save you the headache of vetting dozens of companies, I’ve evaluated the top local exterminators to help you find the most trusted mice control services in San Antonio. Read on for my reviews of the most reliable options available today.
How much do mice control services cost in San Antonio?
Mice control in San Antonio typically ranges from $45 to $75 per month for ongoing maintenance to as much as $2,500 for severe infestations requiring extensive sanitization and repairs.
| Service Type | Estimated Cost |
| Monthly Maintenance | $45 – $75 / month |
| One-Time Removal | $225 average |
| Comprehensive Exclusion/Repairs | $300 – $600+ |
| Extreme Infestations | $500 – $2,500+ |
1. Orkin

Website: https://www.orkin.com/locations/texas-tx/san-antonio-pest-control/branch-776
Address: 10443 Gulfdale St Ste 110
Contact: 726-226-5431
Hours: Available 24/7
When a pest problem feels overwhelming, turning to a company with over 120 years of proven industry experience can offer immediate peace of mind.
Orkin leverages this deep historical knowledge, alongside its proprietary Assess, Implement, and Monitor (A.I.M.) process, to tackle severe infestations systematically.
This structured, science-based approach ensures that technicians not only lay traps but also customize the treatment to your specific property layout.
I found that their focus on comprehensive exclusion is particularly valuable for historic San Antonio properties with tricky structural gaps. For instance, technicians work to seal every potential entry point to prevent future breaches.
The premium nature of their service does come with a notable downside, however. Several clients have noted that treatment plans are quite expensive relative to the initial results.
Obtaining timely responses regarding scheduling mix-ups can be frustrating, so you’ll need to be patient.
amazing!
Annie was amazing! Our house is currently vacant and she noticed evidence of rodent droppings. She immediately called me and said the she was notifying the office to schedule an inspection to handle the problem!
– Michelle perez-montes | Google Review
Went beyond what I expected
I had a rodent problem in my attic and Orkin did an amazing job cleaning it up, removing all of the old insulation and laying in new insulation. It only took two days and the men doing the work were polite, professional and went beyond what I expected.
-Kevin McGlothlin | Google Review
2. Anytime Pest Elimination San Antonio

Website: https://www.anytimepestelimination.com/
Address: 8114 City Base Landing Ste 116
Contact: 210-343-5434
Hours: Mon to Fri, 8 AM–6 PM; Sat: 8 AM–12 PM
Committing to a year-long pest subscription isn’t always ideal when you just have a sudden, isolated rodent visitor.
Anytime Pest Elimination stands out by offering a flexible, no-contract pest control model alongside free, comprehensive inspections.
Their method focuses on proactive trapping and executing thorough exclusion work to ensure the property is fully secured.
I also like the inclusion of a robust service guarantee, which covers free return visits if the mice reappear, making their one-time treatments much less risky.
When I spoke directly to a previous customer, they were incredibly relieved to get a one-time emergency treatment without being locked into a recurring monthly fee.
Unfortunately, their back-office coordination sometimes falls short, with instances where initial appointments were mishandled, and technicians arrived without a proactive courtesy call.
very polite and professional
We had a great experience using Anytime Pest Services. Our technician Gilbert was very polite and professional. He also explained very well what needed to be done for our mice problem. He did an excellent job. Thank you!
-Frieda C | Google Review
saw immediate results with our rodent issues
Santos the tech was amazing! Definitely saw immediate results with our rodent issues in our office as well as the premises! I highly recommend this company!
Mark is also very courteous and professional! I highly recommend this company
-lisa criollos | Google Review
3. X Out Pest Services

Website: https://xoutpest.com/
Address: 8611 Honiley Street
Contact: (726) 888-7020
Hours: Available 24/7
Protecting a household with curious pets and children requires an exterminator who prioritizes safety above all else.
X Out Pest Services meets this need by using family- and pet-friendly treatment methods, along with a strong multi-layer guarantee that includes free re-services and money-back guarantees.
I love how their approach avoids hazardous indoor baiting, focusing instead on targeted nesting treatments and ongoing exterior barriers to keep rodents away.
This prevention-focused exterior barrier method is highly effective for maintaining a clean perimeter around San Antonio homes as well. Plus, their technicians are well-versed in handling local rodent behaviors to ensure long-term protection.
Despite their high reported effectiveness metrics, their service delivery isn’t entirely flawless. For instance, some clients have experienced missed or inconsistent appointment scheduling.
It’s better to call them, too, since the customer service staff has a frustrating tendency to ignore text-based communication preferences in favor of phone calls.
professional and friendly
Listened carefully as I explained my needs. In filling those needs, recognized other issues I wasn’t aware of (mice, for example), communicated with me and took steps to correct these issues. Fully explained the service plan I was purchasing in clear terms. The service techs were professional and friendly. Whole process exceeded my expectations, keeping both family, home and pets safe. Pix is my new mouse trap.
-D Tapley | Google Review
Very thorough
Wild life tech, Josh, was wonderful. Very, very knowledgeable as he has been doing this for years. Totally non judgemental, as dealing with an rat issue is not something one wants to scream from the roof tops 😳. Very thorough, as he shared everywhere around my property they could be coming from, which I thought I had already checked, but he solidified it for me. Thanks to X out Pest services and to Josh!!
-Shirley Perez| Google Review
4. Beeline Pest Control | San Antonio, Texas

Website: https://texasbeeline.com/
Address: 4704 Broom Street
Contact: 210-739-1320
Hours: Mon to Fri: 7:30 AM–7 PM, Sat: 7:30 AM–1 PM
Navigating the costs of home maintenance can be stressful, especially when unexpected exterminator bills start piling up. Beeline Pest Control addresses this anxiety head-on by offering free inspections and customized treatment plans.
Operating as a local, family-owned business gives them a distinct edge in understanding regional pest behaviors.
I noted that they prioritize a preventive approach, heavily emphasizing sealing entry points and eliminating outdoor food sources to keep mice away permanently. They even explicitly back their work with a transparent, no-hidden-charges policy.
When I tried their consultation process for a suspected attic issue last year, I appreciated how clearly the technician broke down the pricing before touching a single tool.
While their pricing is highly competitive, some property owners have reported that technicians occasionally arrive without the necessary materials to complete the job in one go, requiring frustrating follow-up visits.
very knowledgeable
Excellent service. I have quarterly service and have had no issues with insects in my home. Steven the tech addressed a concern regarding mice/rats. He was very knowledgeable and set up 6 bait traps. He will return in one month to check the traps even though I only receive quarterly service. Now that’s just super service.
-Steven Horowitz| Google Review
excellent at his job
I have been using Beeline Pest Control for a few years. George is our technician. He’s excellent at his job and can tell me right away what kind of bugs/pests we have. We also have exterior protection against mice/rats ever since we came home after a vacation and found mice nesting in our bedroom dresser drawers. Now we can take a vacation and know there won’t be unwanted pests when we get home. Thank you, Beeline Pest Control for all you do.
– TravelBug Susan | Google Review
5. Terminix

Website: https://www.terminix.com/exterminators/tx/san-antonio-2406/
Address: 10022 N IH 35
Contact: (210) 946-1167
Hours: Available 24/7
Securing a home against recurring infestations requires heavy-duty interventions and unshakable service warranties.
Terminix delivers on both fronts through their “Terminix It Guarantee,” which provides free return visits at no extra cost, and their advanced Flexi Armour sealing system.
I like how this specialized exclusion technology utilizes highly durable, weather-resistant materials to physically block gaps. With this in place, it’s incredibly difficult for mice to chew their way back inside.
Overall, this team’s strategy relies on an Integrated Pest Management (IPM) approach that carefully balances targeted treatments with reduced reliance on chemicals.
Through this end-to-end control, comprehensive removal and meticulous exclusion to keep properties fully secure are tackled.
However, even with Terminix’s 95 years of national expertise, customers have occasionally noted that the delivered exclusion work didn’t fully align with the initially contracted scope, making the relatively high service cost feel unwarranted.
the best money I’ve spent in a long time
I want to thank Edward Perez with Terminix San Antonio for his professional and prompt service. This rodent control package is the best money I’ve spent in a long time. Edward has been here several times to set traps and remove the culprit. It just takes a phone call and he’s setting up the appointment.
-Cathy Cordes | Google Review
very satisfied with his professional work
Robert is the best technician, he is very responsible and great communication! He completely resolved the issue of the rodent entries.. I am very satisfied with his professional work. Highly recommend Robert!! Thank you so much!!!
-Aya Banes| Google Review





