When you run a business, a messy space isn’t just annoying, but it can actually cost you customers. Dusty desks and bathrooms that look questionable at best don’t exactly scream “professional.”
A friend of mine learned this the hard way when his office tried handling cleaning duties themselves. Let’s just say the pantry didn’t survive, and neither did team morale. He eventually admitted he needed a real janitorial service—not a rotating chore chart.
If you’re in the same boat, you’ll want to know which cleaning teams actually show up and get the job done right.
That’s why I put together this list of the best janitorial services in San Antonio, so you can skip the frustration and get straight to a cleaner, calmer workspace.
How much do janitorial services cost in San Antonio?
Janitorial services in San Antonio cost $25–$60 per hour, or $0.17–$0.41 per square foot. Monthly office cleaning costs range from $200 to $2,000+, depending on the size and frequency of the service.
1. Anago Commercial Cleaning

Address: 23705 I-10, Suite 300, 78257
Contact Details: +1 210-529-8457
Operating Hours:
- Open 24 hours daily
With over 30 years of industry expertise, Anago Commercial Cleaning has built a solid reputation for delivering exceptional janitorial solutions tailored to the needs of businesses big and small.
Unlike many services that push a standard package, Anago takes the time to match its work to your office size, layout, and specific needs. You’re not paying for unnecessary services.
I also liked their Protection+ Disinfection® program. The three-tiered disinfection approach gives businesses the flexibility to scale sanitation based on their environment.
The use of electrostatic spraying and hospital-grade disinfectants makes it clear they’re serious about reducing germs, which is a huge plus in today’s office environment.
Another standout is their emphasis on green cleaning. Their EPA-approved products are not only effective but safer for employees and clients, which shows they’re thinking beyond just appearance.
While Anago’s custom plans are flexible, the full Protection+ program can be pricey. If you don’t need all three disinfection tiers, you may end up paying more than necessary.
Very positive experience from the very beginning
“I’ve been a franchisee in Anago for almost two years, and I’ve had a very positive experience from the very beginning, growing my business. Yesterday, we received an excellent presentation from Mr. Juan Cantoni, Anago’s Regional Director. Thank you for sharing your experience and encouraging us to continue moving forward.”
– Ailin Diaz Martel, Google Review
Thorough job cleaning
“Anago is a great company to work with. They do a thorough job cleaning, are very timely with replies to our needs, and go above and beyond to make sure we are happy with their services. I highly recommend them!”
– Tracy Tindall, Google Review
2. Vanguard Cleaning Systems of San Antonio

Address: 1638 Lockhill Selma Rd, 78213
Contact Details: +1 210-525-0710
Operating Hours:
- Monday to Friday – 9:00 AM to 5:00 PM
- Saturday to Sunday – Closed
Vanguard Cleaning Systems is all about flexibility, tailoring its services to each client. They serve a wide variety of sectors. This includes medical and healthcare, industrial/warehouse, and even car dealerships.
Their disinfection services receive particularly high marks, especially in healthcare offices and busy commercial environments.
One facility manager I spoke with noticed a significant improvement in hygiene after Vanguard implemented electrostatic spraying and intensive high-touch-point cleaning.
These aren’t your average surface-level measures, as they’re thoughtfully designed to reduce the spread of germs in environments where cleanliness is crucial.
But Vanguard doesn’t stop at the basics. Their services extend to comprehensive cleaning solutions, including floor care, window washing, and power washing.
They even use green cleaning products, keeping spaces safe for employees while being environmentally conscious.
But it’s worth noting that Vanguard operates as a franchise, so service quality can vary depending on the specific team assigned to your account.
Outstanding results
“Thank you Priscilla for the recommendation. Pablo Banegas. He did the amazing work o. The strip and wax of our office floors. The results are outstanding-the floors are so shiny they look like mirrors! The entire office looks clean, professional, and truly stands out now. We really appreciate your attention to detail and the quality of work.Thanks again.”
– Erica Cornejo, Google Review
More than happy to accommodate
“Been using Vanguard Cleaning Services for almost a year now, at my facility. Cleaning is something done behind the scenes, but everyone appreciates. Whenever a little project pops up that isn’t in the routine work scope, Vanguard techs are more than happy to accommodate. Vanguard has taken a work load off my shoulders and i cant thank them enough. Highly recommended.”
– Hiverwise, Google Review
3. Upright Cleaning, LLC

Address: P.O. Box 769164
Contact Details: 210-778-2847
Operating Hours:
- Monday to Saturday – 8:00 AM to 7:00 PM
- Sunday – Closed
Upright Cleaning, LLC’s founder, Emily Rhodes, brings over 10 years of experience in facilities support and construction-site cleanups.
The company also has a history of working on Job Order Contracting (JOC) projects with the City of San Antonio, which adds an extra layer of credibility.
They offer flexible cleaning schedules ranging from daily to monthly, tailored to each facility’s unique needs. Their expertise in post-construction and construction-site cleanups sets them apart from many standard janitorial companies.
One local contractor I spoke with praised Upright for handling a recent office renovation cleanup with precision and speed, leaving floors and high-touch areas spotless.
Upright also demonstrates an all-encompassing approach to disinfection and maintenance. Their services include intensive floor care and pressure washing, all complemented by green cleaning products.
However, as a smaller, locally focused company, Upright Cleaning isn’t accredited by the BBB. While this hasn’t impacted the quality for clients I interviewed, prospective customers may want to request references and verify recent projects before committing.
Very responsive, goes above and beyond
“Upright has been doing a great job cleaning our 30,000sqft facility. Emily and her team are very responsive and they go above and beyond to answer any questions or concerns that might come up. Her crew has been very professional and trustworthy. I would have no hesitations in recommending them for either a deep clean or a more frequent cleaning service.”
– Douglas Vignes, Google Review
Reliable, professionally staffed, and complete work on time
“I would highly recommend Upright Cleaning for all your commercial cleaning needs. Extremely reliable, professionally staffed and complete work in a timely manner. Emily has always been able to meet my schedule, even on very short notice. She cares deeply about the quality of her work, her employees, and most of all, she cares about making me look good by making my projects shine! You can’t go wrong with Emily and Upright Cleaning-Jerry, Commercial Construction Superintendent”
– Douglas Sorensen, Google Review
4. Enviro-Master of San Antonio

Address: 5405 Bandera Rd #128, 78238
Contact Details: +1 210-864-1301
Operating Hours:
- Monday to Friday – 9:00 AM to 5:00 PM
- Saturday to Sunday – Closed
Enviro‑Master of San Antonio impressed me with its strong focus on hygiene and safety. Their health‑safety technicians are trained to use commercial‑grade disinfectants and to follow strict safety protocols.
Their Restroom & Hygiene Service stood out as more than just a routine clean. The deep disinfection, restocking of fixtures, and the use of hospital-grade germ-killing products in high-risk areas make a noticeable difference.
Beyond restrooms, Enviro-Master also offers tile and grout deep cleaning and drain treatments. These services address embedded dirt, bacteria, and odors. This is particularly useful in restaurants and other facilities with heavy drain use.
I appreciated seeing their attention to these details. It’s clear they focus on long-term cleanliness rather than just surface-level appearance.
However, some of their advanced services, like electrostatic disinfection and power washing, can be considerably more expensive than standard janitorial work.
For businesses that don’t require high-level disinfection or specialized treatments, it’s worth weighing whether these offerings are necessary.
Everything was properly cleaned and sanitized
“Debbie did an amazing job with the sanitation of our restaurant. From start to finish, she was thorough, dependable, and clearly takes great pride in her work. Every area was left spotless, and we truly appreciated the attention to detail. It gave us peace of mind knowing everything was properly cleaned and sanitized, especially in a setting where cleanliness is so important. We are very satisfied with the results, and if you’re in need of high-quality sanitation services, we highly recommend Debbie!”
– Lauren Billings, Google Review
Impressive attention to detail
“Debbie at Enviro-Master of San Antonio is outstanding! She is professional, friendly, and goes above and beyond to ensure the job is done right. Her attention to detail and commitment to customer satisfaction make her a pleasure to work with. I highly recommend her services!”
– Ledgin Germany, Google Review
5. 1st Call Cleaning Services

Address: 10862 Gulfdale St, 78216
Contact Details: +1 210-421-5011
Operating Hours:
- Monday to Friday – 8:00 AM to 5:00 PM
- Saturday to Sunday – Closed
Founded by U.S. Army veteran Robert Sparrow, 1st Call Cleaning Services is a locally rooted company rather than a national franchise.
They don’t require long-term contracts and even offer a 14-day free trial for facilities—a rare perk not every company offers. Keep in mind, though, the trial is limited to spaces up to 2,000 sq ft, so very large buildings may not fully benefit.
Their janitorial offerings are thorough. It covers daily or nightly cleaning, day porter service, and floor care, including stripping and window cleaning.
What impresses me even more is their electrostatic disinfection service. In spaces with high-touch surfaces, like medical offices or busy workplaces, this really gives peace of mind that germs are being addressed properly.
I also like that 1st Call conducts scheduled on-site inspections.
Always done excellent work in cleaning
“The company I work for has been using 1st Call Cleaning Services for over 5 year and they have always done excellent work in cleaning our new homes! Staff is professional, reliable and they go above and beyond to satisfy their customers. Highly recommend.”
– Rose Pena, Google Review
Always punctual, professional, and thorough
“We couldn’t be happier with the cleaning services provided by 1st Call Cleaning Services. Their team is always punctual, professional, and thorough in their work.
From day one, they’ve shown a keen attention to detail, ensuring every corner of our workspace is spotless. We notice a difference every Monday morning when we walk into our office! It’s clear that they take great pride in their work and genuinely care about customer satisfaction. If you’re looking for a reliable and efficient cleaning service for your office, we highly recommend them!”
– You Name It Specialties, Inc., Google Review





