Living in San Antonio means enjoying the River Walk and breakfast tacos, not scrubbing grout lines on a beautiful Saturday.
Busy professionals want their weekends back, while Airbnb hosts and property managers rely on professional cleaners to keep listings guest-ready between stays.
For both, a reliable cleaner changes the game. But letting a stranger into your personal space requires a serious level of trust.
We’ve scoured the city to find services that bring professional polish, specialized tools, and trustworthy staff to your home. We found teams that scrub with medical-grade precision and others that focus on plant-based products safe for your pets.
Here is our list of the best cleaning services in San Antonio to help you reclaim your weekends.
How much does a cleaning service cost in San Antonio?
Pricing in San Antonio can feel a bit like the weather, varying wildly depending on what is happening. Generally, you should expect to budget somewhere between $20 and $50 per hour for general maintenance.
If you have a 2,000-square-foot home that needs a serious deep clean, flat rates often land between $300 and $700. Keep in mind that specialized add-ons like window washing or carpet shampooing will push that total higher.
The final price tag depends on the size of your space and if you book a quick dust-up or a total overhaul.
1. OCD Cleaners – House Cleaning Service San Antonio

Website: https://texasocdcleaners.com/
Address: 7607 Grissom Rd Ste 105
Contact: +1 210-730-8067
Schedule: Open 24 Hours
OCD Cleaners sets the bar high by using medical-grade supplies and offering an “untimed” deep cleaning service that prioritizes results over the clock. You hire this team when you want cleaners who stay until the job is done, rather than rushing off to the next appointment.
They utilize a detailed 5-to-6-hour process for those deep cleans. This ensures that neglected areas like window latches and bathroom grout get the attention they deserve.
They also offer a free custom assessment to tailor the plan to your specific needs.
However, their policy is generally strict for the whole house. If you were hoping to just get the kitchen and living room tidied up, you might need to look elsewhere.
Nevertheless, their dedication to a medical-grade standard makes them one of the top choices for hygiene-conscious homeowners.
They gave my home and my family back our peace.
Ms. Ivana and Vanessa and the entire team from start to finish was beyond amazing. I am now a lifetime client. They gave my home and my family back our peace. Pictures include a before from my worst room and the after beautifulness. Thank you 🙏
– Jacqueline, Google Review
Anthony and his crew absolutely crushed it.
Anthony and his crew absolutely crushed it. They came in and made my house look brand new. I’m talking top-to-bottom, no corners cut, just straight excellence. The whole place feels refreshed and elevated. Super professional, efficient, and worth every penny. We live a very busy life with two very active children and an infant. So, I signed up for their bi-weekly service! Im so grateful!
– Torrence & Shaz Furlough, Google Review
2. Sparkly Maid San Antonio Cleaning Services

Website: https://www.sparklymaidsanantonio.com/
Address: 200 Main Plaza Suite 420
Contact: +1 210-664-5052
Schedule: Open 24 Hours
Sparkly Maid stands out with a 24-hour satisfaction guarantee and a commitment to using eco-friendly green cleaning products at no extra charge.
This locally owned, Latina-led business feels much more personal than the big national franchises.
Their flat-rate pricing model is also a huge relief. This means you won’t have to worry about surprise fees tacked on at the end of the service.
The team arrives fully equipped with safe, non-toxic supplies that are great for homes with pets or kids.
When I spoke to their scheduling team, they were incredibly helpful in explaining how their background checks work for the cleaners. It gave me a lot of confidence in their security protocols.
Just be aware that if your schedule changes, you need to give them 48 hours’ notice. Rescheduling with less time than that will likely incur a fee.
Everything is spotless and refreshed.
Fantastic results! This was my first time hiring a cleaning service and we were very impressed. Briseida was punctual and worked very hard for 3 hours deep cleaning our home. Everything is spotless and refreshed. The best part is that the house does not smell like strong chemicals, just clean! Definitely will rebook services in the future and recommend to others.
– Winter Zamora, Google Review
I had a fantastic experience with Sparkle Cleaning
I had a fantastic experience with Sparkle Cleaning, thanks to Claudia B! She arrived right on time and immediately put me at ease—taking a big task off my plate with professionalism and care. Claudia worked incredibly hard and her attention to detail showed in the results. Beyond the spotless space, her friendly attitude made the whole experience smooth and stress-free. Highly recommend her and the Sparkle team!
– Karina Miller, Google Review
3. Maids on a Mission

Website: https://www.maidsonamissionus.com/
Address: 10864 Gulfdale St
Contact: +1 210-988-0288
Schedule: Mon – Fri: 8 AM – 5 PM
Maids on a Mission operates as a veteran-run and woman-owned business that prioritizes its employees’ well-being. Unlike many gig-economy apps, they provide their cleaners with medical benefits and a living wage.
This seems to result in a dedicated team that actually cares about your home. They even have cleaning checklists informing you exactly what tasks are included, from removing cobwebs to polishing stainless steel.
Remarkably, they seem to be very much involved in the community in several ways.
One, they support first responders with not-for-profit cleanings. They also partner with “Cleaning For A Reason” to help cancer patients, which shows a lot of heart
The biggest downside for some working professionals is their schedule. They do not work weekends, so you must be available or provide access between Monday and Friday.
They are very responsive to texts to accommodate our schedule
We have been using their services since having our second child and it has been wonderful. They are very responsive to texts to accommodate our schedule and the cleaning techs have been superb! Sandra did a very thorough job after the holidays getting our home back to normal and went over her allotted time to do so!
I love Maids on a Mission!
I love Maids on a Mission! Misha, Brittany & Turquoise have all been amazing!! They have worked around our crazy schedule & crazy household to bring peace to my mind!!! I am so grateful to have found such a reliable service. Thank you!
– Lisa Alba, Google Review
4. Molly Maid of San Antonio-Northwest

Website: https://www.mollymaid.com/locations/texas/helotes/
Address: 8131 I-10 Suite 115
Contact: +1 210-762-6235
Schedule:
- Mon – Fri: 6 AM – 1 AM
- Sat: 6 AM – 10 PM
- Sun: 7 AM – 8 PM
Molly Maid offers the reliability of a large established brand with their “Neighborly Done Right Promise” and a flexible policy of no term contracts. This means you aren’t locked into a long-term commitment if your needs change, which offers great peace of mind.
They also arrive with a very specific 44-point cleaning checklist. Their team works systematically, wiping down baseboards and dusting ceiling fans.
I also love that their support for domestic violence victims through the Ms. Molly Foundation adds a layer of social responsibility to their work.
One potential drawback you may want to consider is their standard operating hours for regular service.
While the office contact hours are long, the primary cleaning slots are usually only on weekdays from 8 a.m. to 5 p.m. This might make it tricky if you prefer evening appointments.
The work they did was thorough and outstanding.
Ruby and Valerie were amazing. The work they did was thorough and outstanding. I couldn’t have asked for better service. I highly recommend asking for these ladies when you book a service. They are valuable assets to this company who should be appreciated for the quality work that they do.
– Karen Conlin, Google Review
They went above and beyond my expectations.
The team arrived promptly and immediately went to work. They went above and beyond my expectations. They were able to turn around my 2/2 1200 sq ft apt in a little under 3.5 hours. I would recommend the service to anyone needing move out deep cleaning. Very thankful to the team sent.
– Walter Hidalgo, Google Review
5. Lupe’s Home & Office Cleaning, LLC

Website: https://mylupeshousecleaning.co/
Address: 2618 S Presa St
Contact: +1 210-942-7242
Schedule: Mon – Fri: 8 AM – 5 PM
What’s notable about Lupe’s Home & Office Cleaning is how they employ full-time staff rather than random independent contractors. Doing so ensures clients see familiar faces and receive the same standard of work at every visit.
Since they’ve been family-operated since 1999, that legacy really shows in their attention to detail.
I also loved that when I called them recently, I spoke to a real human who knew exactly what was going on, rather than getting stuck in a loop with an automated bot.
Plus, they bring all their own supplies, which is one less headache for you.
They do offer a satisfaction guarantee, but there is a catch. If you spot a missed area, you have to be quick.
To claim a free re-clean, you must report the issue within a tight 24-hour window. But for the reliability they offer, that’s a fair trade-off.
The Blue Team did an excellent job.
The Blue Team did an excellent job. Within the hour limit, they accomplished the tasks I needed – cleaning the window blinds, cleaning the light fixture, and the ceiling fans. They were even able to clean the living room floor. Very happy with their work and they were very polite and friendly. Will ask for the Blue Team again for next time. Thank you very much!
I’m a satisfied customer! Thanks.
Attentive, very thorough, and friendly, … the cleaning ladies have an eye for details! Mel and the team arrived timely and did a great job deep cleaning each room. The office staff is professional and courteous. I’m a satisfied customer! Thanks.





